New research from the Johns Hopkins University found the hemp-derived Delta-8 THC to be less potent than Delta-9 THC, the main psychoactive component in cannabis, when orally ingested, though the former can still produce similar psychoactive effects. Delta-8 resulted in significantly lower ratings of drug effect than Delta-9 at a dose of 20 milligrams…However, doubling the dose of Delta-8 to 40 milligrams resulted in the same rates of drug effects as 20 milligrams of Delta-9. The clinical trial focused on 19 healthy adults with no past-month exposure to cannabinoids.