Systematically Testing the Evidence on Marijuana

Some cannabis works about as well as ibuprofen against chronic pain, OHSU-led review finds

Source: Oregon Public Broadcasting

Jan 6, 2026 | Research

A systematic review of studies evaluating cannabis as a pain treatment concluded that some cannabis products do likely work to reduce chronic pain a little bit. The review, which was led by OHSU researchers and published in the Annals of Internal Medicine, analyzed the results of 25 randomized controlled trials of cannabis as a pain treatment in Europe, the United States and Canada. It was funded by the U.S. Department of Health and Human Services, as a follow-up to an earlier synthesis of the evidence on cannabis and pain.

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